Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional
Official Title:
Brief Summary: Threatened miscarriage is manifested by vaginal bleeding, with or without abdominal pain, while the cervix is closed and the fetus is viable and inside the uterine cavity.Threatened miscarriage is a common complication of pregnancy occurring in 20% of all clinically recognized pregnancies and about half of these will eventually result in pregnancy loss.Micronized progesterone which is used in a range of indications including infertility due to luteal insufficiency and threatened and habitual abortion, has a similar molecular structure and pharmacological effects to endogenous progesterone.Chinese Herbal Medicines is a part of Traditional Chinese Medicines and has been widely used for the treatment of miscarriage in China and other Asian countries for centuries.CHM have become very popular alternative to Western medicines and are commonly used as an alternative treatment for threatened miscarriage.Amongst all the causes for threatened miscarriage, "Kidney Deficiency" is the most important cause leading to threatened miscarriage and "Shou Tai Pill" is the most frequently used formula (72.0%) to treat threatened miscarriage.This basic formula is made up of four individual Chinese medicines, including Chinese Dodder Seed (Semen Cuscuta), Chinese Taxillus Twig (Flerlia Taxillus), Himalayan Teasel Root (Radix Dipsaci), and Donkey-hide Glue (Colla Corii Asini).Furthermore, supplementary of Common/Wingde Yan Rhizoma in the formula can enhance the therapeutic effects by further strengthening kidney of pregnant women.The goal of this double-bind, randomized and double dummy controlled trial is to determine which of the two oral medications, CHM or Micronized progesterone, and will mostly likely result in live birth in women with threatened miscarriage.