Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional
Official Title: Randomized Trial of Oral Dexamethasone for Acute Chest Syndrome
Brief Summary: People with sickle cell disease (SCD) may develop acute chest syndrome (ACS), which is a common and serious lung condition that usually requires hospitalization. Dexamethasone is a medication that may decrease hospitalization time for people with ACS, but it may also bring about new sickle cell pain. This study will evaluate the effectiveness of a dexamethasone regimen that includes a gradual dose reduction at decreasing hospitalization and recovery time in people with SCD and ACS.