Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Treating Adjustment Disorders Stemming From Romantic Betrayals: An Open-label Trial of Impairing Memory Reconsolidation Using Propranolol
Brief Summary: Attachment injuries are events occurring within couple relationships that involve betrayal or abandonment by a significant other during times of need (e.g., infidelity). They can be understood as relationship traumas, which can lead to debilitating symptoms consistent with posttraumatic stress disorder (PTSD), depression, and generalized anxiety for the injured partner. Research has demonstrated that the presence of an attachment injury represents a barrier to empirically effective couple's therapy. However, disrupting memory reconsolidation with the beta-blocker propranolol has been shown to alleviate PTSD symptoms by attenuating the salience of the emotional trauma memory, representing an interesting avenue for the treatment of adjustment disorders stemming from attachment injuries. Here, the investigators aim to extend the conditions under which reconsolidation therapy with propranolol can be used in a clinical setting. The investigators hypothesize that 6 sessions of memory reactivation under propranolol would significantly reduce trauma-related, depression, and anxiety symptom, associated with an attachment injury.