Clinical Trial: Managing Alcoholism in People Who Do Not Respond to Naltrexone

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Non-Response to Naltrexone (NTX): Next Steps in Managing Alcoholism

Brief Summary: This is a study involving treatment for alcohol dependence (alcoholism). The study will combine motivational enhancement therapy and cognitive behavioral therapy (combined behavioral intervention, or CBI) and tests the benefits of continued/discontinued treatment with naltrexone in a randomized placebo-controlled trial. CBI may have advantages in motivating patients to greater medication adherence and may address psychosocial factors that may limit the effects of naltrexone.