Clinical Trial: Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Amblyopia Treatment Study: Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

Brief Summary:

To determine whether the success rate with drug treatment (atropine) of amblyopia due to strabismus or anisometropia in patients less than 7 years old is equivalent to the success rate with occlusion (patching) therapy
To develop more precise estimates of the success rates of amblyopia treatment
To identify factors that may be associated with successful treatment of amblyopia
To collect data on the course of treated amblyopia to provide more precise estimates of treatment effects than are now available

Extended Follow up of Study Patients

Primary: To determine the long-term visual acuity outcome at age 10 years and at age 15 years in patients diagnosed with amblyopia before age 7 years.
Secondary: To determine whether the long-term visual acuity outcome at age 10 years and at age 15 years differs between patients who received patching followed by best clinical care and patients who received atropine followed by best clinical care