Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: A Dose-escalation Tolerability Study of Levodopa/Carbidopa in Angelman Syndrome
Brief Summary:
This study is designed to determine the highest dose of levodopa/carbidopa that can be tolerated without any serious side effects by children with Angelman syndrome.
It has been hypothesized that levodopa may lead to an improvement in the neurodevelopment and abnormal movements (e.g. tremors) in children with Angelman syndrome.
Data from this study will be used to design a phase II trial to determine the efficacy of levodopa in treating children with Angelman syndrome.