Clinical Trial: Reduced Intensity Conditioning in Patients Aged ≤35 With Non-Malignant Disorders Undergoing UCBT, BMT, or PBSCT

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: A Phase II Study of Reduced Intensity Conditioning in Patients ≤35 Years of Age With Non-Malignant Disorders Undergoing Umbilical Cord Blood, Bone Marrow, or Peripheral Blood Stem Cell Transplan

Brief Summary: The objective of this study is to demonstrate the efficacy of using a reduced-intensity condition regimen with UCBT, double cord UCBT, matched unrelated donor (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders that are amenable to treatment with HSCT. After transplant, subjects will be followed for late effects and for ongoing graft success.