Clinical Trial: Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Phase II Study of Bevacizumab and Vorinostat for Recurrent WHO Grade IV Malignant Glioma Patients

Brief Summary: It has been shown that bevacizumab has significant anti-tumor activity in patients with recurrent glioblastoma multiforme. Vorinostat has modest anti-tumor activity against malignant glioma and can enhance the action of both chemotherapy and anti-angiogenics. Patients will be treated with a combination of bevacizumab and vorinostat.