Clinical Trial: Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis

Brief Summary:

This is a phase III trial to determine whether adjunctive sertraline will lead to improved survival 18-week survival.

There was an initial phase I/II unmasked dose finding pharmacokinetic study of CSF concentrations in 172 persons conducted from August 2013 to August 2014.