Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL
Official Title: Effects of Opioid Use Disorder and Non-fatal Overdose on Tau Pathology; a [18F]PI-2620 PET/CT Study
Brief Summary:
The investigators plan to enroll up to 60 adult subjects in this study.
There will be three groups of up to 20 subjects each in this study.
Group 1: individuals with OUD and a history of at least one opioid-related OD in the past year that required naloxone treatment reversal: OUD/OD+ Group 2: individuals with OUD without a lifetime history of opioid-related OD OUD/OD- Group 3: Healthy controls without a lifetime OUD: HCs PET/CT imaging will be used to evaluate the uptake of tau in the brain using the investigational radiotracer [18F]PI-2620.
Each subject will have one [18F]PI-2620 positron emission tomography/computed tomography (PET/CT) scan performed.