Clinical Trial: Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL




Official Title: Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

Brief Summary:

This is a placebo-controlled, multi-arm phase II platform screening trial designed to test the safety, pain responses, and pharmacodynamic activity of multiple experimental therapies simultaneously in participants with moderate-to-severe pain due to schwannomatosis (SWN).

This Master Study is being conducted as a platform that may allow participants with pain associated with schwannomatosis to receive a novel intervention throughout this study.
Embedded within the Master Study are individual drug sub-studies:

  • Investigational Drug Sub-Study A: Siltuximab
  • Investigation Drug Sub-Study B: Erenumab-Aooe