Clinical Trial: Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

Study Status: NOT_YET_RECRUITING
Recruit Status: NOT_YET_RECRUITING
Study Type: INTERVENTIONAL




Official Title: Adaptive Working Memory and Physical Exercise Training to Improve Brain and Mitochondrial Function in MCI

Brief Summary: The prevalence of dementia will double in the next three decades in the U.S.; effective treatment or prevention for dementia is urgently needed.
The current exploratory project aims to evaluate and understand how the brain and cognition may improve after a 12-week intervention that combines brain training and aerobic exercise training to improve brain function, both in those with mild cognitive impairment (some with possible prodromal Alzheimer's disease) and with healthy aging.
Findings from this pilot project will guide and refine the development of a future larger clinical trial that aligns with the goals of the National Alzheimer's Plan of Action (NAPA), especially regarding "Prevent and Effectively Treat Alzheimer's Disease (AD) by 2025.