Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Development of Medication Reconciliation Using Electronic Pharmaceutical Record: a National Multicenter, Cluster-randomized, Two-period Crossover Study in Elderly Hospitalized in Geriatrics, Internal
Brief Summary:
Context Adverse drug events (ADEs) may occur in hospitalized patients and may result from discrepancies between patient's current medications and the drugs prescribed at admission (omission, commission, dosing errors….). Consequences of these discrepancies may be mild (e.g. isolated biological abnormalities), but may also lead to severe clinical outcomes. Medication reconciliation is a process of creating the most accurate list of patient's current medication in order to decrease discrepancies and eventually ADEs. Information technology and electronic health records are of great interest in this process. In France, medications dispensed in community pharmacies during the past 4 months are registered in patient's electronic pharmaceutical record. The impact of this record together with a pharmacist medication reconciliation will be tested in the CONCIPAGE study.
Design The CONCIPAGE study is a national, multicenter, cluster-randomized, two-period cross-over study. It will estimate the impact of a medication reconciliation, made by a pharmacist, using patient pharmaceutical record, on the occurrence of ADEs during the hospitalization of patients aged 65 years and over.
Fifteen hospitals gathering 20 centers (8 geriatric departments, 8 internal medicine departments, and 4 orthopedic surgery departments) will participate in the study. An equilibrated randomization will be applied to the 20 centers. The recruiting period will last for 24 months and will be divided into four 6-month consecutive periods (A, B, C, D). During the first 6-month period (period A), 5 centers (1 to 5) will apply one strategy (intervention or usual care) while 5 others (6 to 10) will apply the alternative strategy. Centers 11 to 20 will not recruit patients during period A. During the next period (period B), centers 11 to 15 and 16 to 20 will appl