Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine: Study 1
Brief Summary: The purpose of this study is to determine whether maintenance on different oral doses of sustained release d-amphetamine (SR-AMP) combined with constant-dose sublingual buprenorphine (BUP) is safe and well tolerated and decreases self-administration of cocaine alone or combined with hydromorphone (HYD). Secondary aims are to determine whether SR-AMP attenuates the subjective and physiological effects of cocaine during drug sampling periods prior to choice opportunities.