Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: Biobehavioral Study of Opioid Drug Seeking Behavior: Study 4
Brief Summary:
The purpose is to study the extent to which stress and other factors, including money, the amount of drug available and the amount of work effort, affect drug choice.
This study will assess whether exposure to yohimbine, a drug stressor, increases opioid craving- and -seeking behavior. We will determine whether these behavioral outcomes are associated with biobehavioral stress markers: increased saliva cortisol levels, cardiovascular response (heart rate and blood pressure), and negative mood state.