Clinical Trial: Effect of Genetic Association With Functional Dyspepsia and Mood Disorders

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational



Official Title: Effect of Genetic Association With Functional Dyspepsia and Mood Disorders

Brief Summary:

Background:

Functional dyspepsia (FD) is one of the commonest digestive disorders. The pathophysiology of functional dyspepsia is uncertain. Risk factors include genetics, gender, age, helicobacter pylori infection, etc. However, few reported the association of genetic contribution to the development of FD and mood disorder.

Indication:

Functional dyspepsia patients

Study center(s):

Prince of Wales Hospital, Hong Kong

Aims:

  • To evaluate genetic factors on development of functional dyspepsia & common mood disorders
  • To evaluate genetic factors on the severity of function dyspepsia & mood disorders
  • To develop a diagnostic test for classification of functional dyspepsia by plasma ghrelin and serotonin expression
  • To collect sleep data for future use
  • To save blood sample for future retrospective diagnostic or genetic examination

Study design:

Case-control cross sectional study

Number of subjects:

Total of 1200 subjects (300 FD patients + 300 relatives of FD patients FDR) and (300 Controls + 300 FDR)

Patient population:

Functional dyspepsia patients age 18-60