Clinical Trial: Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Characterization of Humoral and Cellular Immunity of Low and High-responders After TBE Vaccination

Brief Summary:

The phenomenon of no- and low-responsiveness has been described after applications of different vaccines (e.g. hepatitis B, TBE) and is concerning about 2-10% of the vaccinees.

The aim of this project is to investigate the humoral and cellular immune responses of low-responders after TBE vaccination in order to find parameters regarding immunoregulation against TBE. It is of interest if non-responsiveness is a general immunological deficit of a distinct patient group or if it is a antigen-specific phenomenon.