Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: OBSERVATIONAL
Official Title: Genital Lichen Sclerosus - Epidemiology, Comorbidities and the Role of Vulvar and Penile Microbiome
Brief Summary:
In genital LSc, three pathological processes are implicated in disease development: inflammation, sclerosis/fibrosis and neoplasia.
The role of genital microbiome is still to be investigated and explained.
Genital LSc microbiome studies are missing.
The ecological community of microorganisms that are present on our body and of the body itself defines the human skin microbiome.
Revealing the genital microbiome may potentially lead to new therapies of genital LSc.
The primary aim is to analyze genital microbiome before and after the treatment (topical corticosteroids or topical calcineurin inhibitors or circumcision) in both male and female patients diagnosed with genital LSc as well as to analyze genital microbiome in healthy (non-genital LSc) controls.
2) The secondary aim is to determine incidence and prevalence of male and female genital LSc in Sweden and its association with other diseases.
The Study will be divided in two parts