Clinical Trial: Achalasia: Mechanisms Underlying Treatment Failure

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational




Official Title: Achalasia; Mechanisms Underlying Persistent Symptoms After Treatment

Brief Summary:

In patients with achalasia, the relationship between the perception of dysphagia, oesophageal emptying, lower oesophageal sphincter (LOS) distensibility and oesophageal circular and longitudinal muscle contraction is not clear.

We aim to characterize oesophageal circumferential and longitudinal muscle contractility and LOS distensibility in patients with achalasia (either before or after treatment). This may allow an understanding of the mechanisms underlying persistent dysphagia and delayed oesophageal emptying after treatment.