Clinical Trial: Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery

Study Status: COMPLETED
Recruit Status: COMPLETED
Study Type: INTERVENTIONAL




Official Title: Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery: A Randomized, Double-blind, Parallel, Placebo-controlled Trial

Brief Summary: Anorectal problems, such as hemorrhoids, fistula, fissures, Etc., often require surgical treatment.
Patients often have postoperative pain after these surgeries, which increases discomfort and hospital length of stay.
The efficacy of oral non-opioids in the treatment of such pain is poor.
Hydromorphone is an opioid analgesic commonly used orally or intravenously for postoperative pain management.
We designed this trial to investigate the efficacy and safety of intrathecal (delivery directly to the spinal cord during spinal anesthesia) single dose hydromorphone versus intrathecal placebo in treating postoperative pain among human subjects after anorectal surgery, but also the recovery of postoperative motor capacity in these human subjects.