Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Lifestyle Intervention in Preparation for Pregnancy (LIPP)
Brief Summary: The objective of this proposal is to break the vicious cycle of obesity/metabolic dysfunction during pregnancy. Lifestyle interventions in obese women during pregnancy have had limited success in improving maternal or offspring short and long-term metabolic health. We propose that lifestyle interventions need to be initiated prior to conception in overweight and obese women (henceforth referred to as obese) in order to first improve maternal metabolism. Lifestyle interventions will take place in the greater Cleveland recreational facilities. Metabolic evaluations will be conducted in the Clinical Research Units of the Case Western Reserve Clinical Translational Science Center (CTSC). We hypothesize this will result in decreased fetal adiposity and improved metabolic function in the offspring.