Study Status: RECRUITING
Recruit Status: RECRUITING
Study Type: INTERVENTIONAL
Official Title: Infrared Thermography Associated With Cutaneous Microcirculation for Detection of Brown-adipose Tissue: Proof of Concept Against PET-CT in Patients Affected by Pheochomocytoma and/or Paragangliom
Brief Summary: Patients affected by pheochromocytoma (PHEO) have brown-adipose tissue (BAT) hyperactivation.
They perform, in routine settings, a FDG PET-CT scan.
The high metabolic activity of BAT and its ability to consume both glucose and fatty acid suggest that it may have potential as a therapeutic target in the treatment of obesity.
However, alternative non-invasive techniques to PET-CT BAT detection still need more validation.
Accordingly, our aim will be to measure the temperature and microcirculation of the skin overlaying BAT depots in the region of FDG-uptake detected by 18F-FDG PET/CT before and after a cold test in PHEO patients.