Clinical Trial: Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Effects of Different Inhalational Anesthetic Agents on the Incidence of Clinical and Subclinical Acute Kidney Injury After Liver Resection Surgery: a Pilot Study
Brief Summary:
- It has been shown that patients who undergo liver resection surgery are at high risk for postoperative acute kidney injury (AKI).
- Sevoflurane may increase the risk for postoperative AKI because of production of compound-A.
- Therefore, we have planned to investigate the effects of different anesthetic agents on postoperative renal function.
- Patients undergoing liver resection surgery are randomized into 2 groups.
- One of the groups receives sevoflurane and the other group receives desflurane.
- Blood and urine specimen are sampled both pre- and postoperatively, and several biomarkers are compared between the groups.