Clinical Trial: Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Giant Cell Myocarditis Treatment Trial Pilot Study

Brief Summary: This is a study to determine the efficacy of muromonab-CD3 and cyclosporine as treatment in patients with giant cell myocarditis (GCM). T lymphocytes appear to be involved in GCM. Muromonab-CD3 has been shown to reduce the number of lymphocytes and cyclosporine inhibits lymphocyte activation. This treatment may prolong patient survival until transplantation or ventricular assist device placement is possible.