Study Status: Active, not recruiting
Recruit Status: Active, not recruiting
Study Type: Interventional
Official Title: Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
Brief Summary: The investigators propose a randomized double blind 8 week treatment trial of intranasal OXT vs. placebo in 24 subjects aged 5 to 18 years with PWS in order to assess IN-OXT's affect (1) Eating behaviors (2) Repetitive and disruptive behaviors (3) social cognition measures and (4) Salivary OXT levels and plasma levels of ghrelin, pancreatic polypeptide and leptin. The investigators will determine if IN-OXT reduces eating behaviors in addition to improving social cognition and reducing repetitive/disruptive behaviors in children with PWS. If superior to placebo, this data will add to the current knowledge that OXT is an effective treatment for hyperphagia as well as other problematic symptomatology of PWS.