Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational
Official Title: PET Imaging and Lymph Node Assessment of IRIS in Persons With AIDS
Brief Summary:
Background:
- Sometimes people with HIV, the virus that causes AIDS, can have new or worsening symptoms soon after starting HIV medications. Often these symptoms are caused by immune reconstitution inflammatory syndrome (IRIS). Researchers want to study why and how people develop IRIS and how best to prevent and treat it.
Objectives:
- To learn the causes and effects of IRIS,and how to best manage it.
Eligibility:
- Adults 18 and older with HIV and low CD4 counts,, about to start HIV medicines; or those already taking HIV medicines with symptoms thought to be related to IRIS.
Design:
<TAB><TAB>- review of medical history<TAB>
<TAB><TAB>- physical and eye exams
<TAB><TAB>- blood, urine, and tuberculosis (TB) tests
<TAB><TAB>- electrocardiogram (EKG)
<TAB><TAB>- chest x-ray