Clinical Trial: A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma

Brief Summary: The purpose of this research is to evaluate the safest and most effective dose of a Food and Drug Administration (FDA) approved drug (XIAFLEX) in the treatment of lipoma (fatty tumors of varying sizes that occur commonly in the adult population). The fat in the lipoma is like normal fat except that it is enclosed in a balloon-like structure which is made of collagen (fibrous tissue). Treatment of the lipoma with an injection of XIAFLEX (a protein that breaks down collagen fibers) may dissolve the collagen/fibrous strands thereby decreasing the size of the lipoma or removing it.