Clinical Trial: Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease

Study Status: Completed
Recruit Status: Completed
Study Type: Observational



Official Title: The Pathogenic Role and Diagnostic Implication of Program Cell Death Receptor 1 Expressed on T Cells in Mycobacterium Avium Complex Lung Disease

Brief Summary:

  1. To understand the components of PBMC in MAC-LD patients, including T cells, B cells, nature killer cells, and monocyte.
  2. To confirm the phenomenon of reduced PBMC response in MAC-LD patients
  3. To study the proportion of apoptosis and PD-1 expression in T cells among MAC-LD patients, MAC colonizers, patients with tuberculosis, and healthy controls.
  4. To study the apoptosis and PD-1/PD-L1 expression in T cells/macrophage from bronchial lavage among MAC-LD patients, MAC colonizers, patients with tuberculosis,
  5. To examine the PD-1 gene polymorphism and the correlation with MAC-LD.