Clinical Trial: Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: A Randomized Double-blind Controlled Pilot Feasibility and Safety Trial of NGAL-directed Sodium Bicarbonate to Protect Renal Function in Patients With the Systemic Inflammatory Response Syndrome,

Brief Summary: The investigators will determine the feasibility, safety and efficacy of intravenous sodium bicarbonate in reducing progression to overt acute renal failure in patients with the systemic inflammatory response syndrome, and low urine output or early acute renal impairment as defined by serum neutrophil gelatinase-associated lipocalin (NGAL).