Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Magnolia Study Prolonged Protection From Bone Disease in Multiple Myeloma. An Open Label Phase 3 Multicenter International Randomised Trial
Brief Summary:
Main hypothesis: Patients who continue zoledronic acid after year 2 have longer time until progression in bone disease compared to patients who stop treatment after two years?
Secondary hypothesis: Serum will bone markers increase prior to progression in bone disease in the individual patient?
Secondary hypothesis: Low-dose CT will detect more cases of osteolytic bone disease in Multiple Myeloma compared to conventional radiography