Clinical Trial: PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional



Official Title: PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial

Brief Summary:

In the proposed trial the investigators will recruit women and men >65 years of age with acute osteoporosis-related pelvic fractures and address 3 specific aims over 3 months of treatment in a placebo controlled double blind study to determine if standard care and teriparatide 20 mcg/day versus placebo for pelvic fractures:

  1. Results in earlier evidence of cortical bridging on routine radiographs followed by confirmatory Focus CT, a novel method to reduce radiation exposure from CT scans (primary outcome).
  2. Leads to a faster reduction in pain as assessed by both the Numeric Rating Scale and a reduction in the use of narcotics (secondary outcome).
  3. Leads more rapidly to improved functional outcome using a short physical performance battery to assess lower extremity function (secondary outcome).