Clinical Trial: Intra-abdominal Pressure and Dynamic Preload Variables

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Observational




Official Title: The Influence of Pneumoperitoneum and Open Abdominal Surgery on Dynamic Preload Variables

Brief Summary:

Dynamic preload variables like pulse-pressure and stroke volume variation may be used to predict fluid responsiveness in patients during controlled ventilation. Previous work has shown that a rapid decrease in intra-abdominal pressure may lead to an increase in dynamic preload parameters, suggestive of a fluid deficit - despite fluid status had not changed [van Lavieren M 2014].

The results of this study are limited by the fact that a non-invasive and uncalibrated hemodynamic monitoring system (Nexfin™) was used.

The present study thus aims to evaluate the effects of abdominal pressure changes on dynamic preload parameters (PPV and SVV) employing conventional, invasive hemodynamic monitoring (Vigileo®, Edwards Lifescience) in open abdominal surgery as well as in minimal invasive surgical procedures with pneumoperitoneum.