Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Interventional
Official Title: Targeting Inter-Hemispheric Alpha Coherence With tACS To Treat PMDD
Brief Summary:
Purpose: Using transcranial alternating current stimulation (tACS), the investigators will study and attempt to treat mood dysregulation in women with premenstrual dysphoric disorder (PMDD).
Participants: Women between ages 18-45 with a diagnosis of PMDD confirmed by participation in a PMDD diagnostic study (IRB# 05-3000).
Procedures (methods): After a re-screening and consent appointment, eligible participants will begin daily ratings and have baseline EEG performed during the follicular and luteal phases. Following the luteal phase EEG, the patient will receive, in a double blind cross-over fashion, 5 days of tACS, 40 minutes/session, performed in two successive months. On the first and fifth days of each treatment, EEG will be performed. Patients' symptoms will be assessed at the end of each session and with the daily mood ratings.