Clinical Trial: Sorbent Therapy of the Cutaneous Porphyrias

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Sorbent Therapy of the Cutaneous Porphyrias

Brief Summary: The investigators demonstrated that cholestyramine is an effective binding agent in vitro for porphyrins. A few isolated case reports of treatment of individuals with a cutaneous porphyria suggest that cholestyramine and colestipol effectively remove porphyrins. Hypothesis: orally administered colestipol will effectively reduce sun sensitivity and lower erythrocyte porphyrin concentrations in subjects with erythropoietic protoporphyria (EPP).