Clinical Trial: Respiratory Muscle Strength and Function in Neuromuscular Disorders and Chronic Obstructive Pulmonary Disease

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational



Official Title: Multimodal Measurement of Respiratory Muscle Strength and Function: Validation of Volitional and Non-volitional Tests With Regard to Nocturnal Hypoventilation in Patients With Neuromuscular Disorders

Brief Summary:

Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to

  • identify disease-specific patterns of respiratory muscle impairment in different NMD and COPD
  • establish which set of tests is predictive of sleep-disordered breathing or daytime hypercapnia in patients with NMD or COPD, respectively.
  • to investigate the decline of respiratory muscle function in patients with progressive NMD and COPD along with sleep studies and capnography