Clinical Trial: Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional




Official Title: Rasagiline (Azilect) - Neuroprotection for Macula-off Retinal Detachment

Brief Summary: This randomised, double-blind, placebo-controlled clinical trial investigates the neuroprotective effect of rasagiline in patients suffering from a retinal detachment affecting central vision. Based on results from a study in mice suffering from retinal degeneration, the investigators hypothesize that rasagiline delays neurodegeneration in the retina and improves visual acuity outcomes after retinal detachment surgery. Rasagiline is a second-generation propargylamine with neuroprotective properties modulating the caspase-dependent pathway of programmed cell death.