Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Ursodeoxycholic Acid (UDCA) as Adjuvant Treatment for Rhegmatogenous Retinal Detachment: a Phase I Pilot Study
Brief Summary:
20 patients presenting a rhegmatogenous retinal detachment with more than 4 days of duration will be prospectively included.
A single dose of ursodeoxycholic acid will be administered orally before surgery at different time-points in 16 subjects. Standard surgery will be performed and ocular samples will be collected during the procedure. Ursodeoxycholic acid treatment will be continued in treated patients during 3 months after surgery.
Ocular and serum samples from the 4 untreated patients will serve as negative controls for the determination of UDCA levels.