Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
Brief Summary:
The IMPRESS trial aims to see whether the improved results can be achieved for patients with pelvic sigmoid cancers by having an MRI scan prior to surgery so that doctors can make the most appropriate treatment choice.
Everyone who agrees to take part will be randomly allocated by one of the research team to either have standard treatment for sigmoid cancer, which involves CT-imaging of chest and abdomen / pelvis before surgery, or to undergo standard treatment, plus an additional MRI scan, before surgery. The additional MRI scan will be the only difference in approach between the two arms of the trial. After all imaging is obtained, patients from both arms will be discussed by the Multidisciplinary Team as usual. An amendment to this study in 2015 allowed for patients with sigmoid cancer who receive an MRI by local indication to be entered into the trial as observational patients, and a new primary endpoint added that compares the rates of high risk features identified between CT and MRI scans for all patients.