Status | Study |
RECRUITING |
Study Name: Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors Condition: Diffuse Intrinsic Pontine Glioma Date: 2023-02-17 Interventions: Courses of weekly intravenous SC-CAR4BRAIN infusions for 3 weeks, then 1 week off |
RECRUITING |
Study Name: FUS Etoposide for DMG - A Feasibility Study Condition: Diffuse Intrinsic Pontine Glioma Date: 2023-02-06 Interventions: Subjects will receive focused ultrasound sonication followed by once daily oral etoposide (50mg/m^2/dose).Oral etoposide will be taken |
Not yet recruiting |
Study Name: Re-Irradiation of Progressive or Recurrent DIPG Condition: Recurrent or Progressive Diffuse Intrinsic Pontine Glioma Date: 2017-04-19 Interventions: Radiation: re-irradiation if DIPG has progressed or recurred at 180 days or later from completion of pri |
Not yet recruiting |
Study Name: CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With DIPG Condition: Diffuse Intrinsic Pontine Glioma Date: 2017-03-16 Interventions: Drug: Convection Enhanced Delivery (CED) of Nanoliposomal irinotecan (nal-IRI) Nal-IRI will be given dir |
Recruiting |
Study Name: International Diffuse Intrinsic Pontine Glioma (DIPG) Registry and Repository Condition: Diffuse Intrinsic Pontine Glioma Date: 2017-03-08 |
Recruiting |
Study Name: Gemcitabine in Newly-Diagnosed Diffuse Intrinsic Pontine Glioma Condition: Diffuse Intrinsic Pontine Glioma Date: 2016-11-29 Interventions: Drug: Gemcitabine Participants receive a one time IV dose of gemcitabine prior to having standard of car |
Active, not recruiting |
Study Name: H3.3K27M Peptide Vaccine for Children With Newly Diagnosed DIPG and Other Gliomas Condition: Diffuse Intrinsic Pontine Glioma Glioma Date: 2016-11-02 Interventions: Biological: K27M peptide K27M peptide vaccine, combined with Tetanus Toxoid peptide, emulsified in monta |
Recruiting |
Study Name: Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines Condition: Diffuse Intrinsic Pontine Glioma Date: 2016-05-31 Interventions: Biological: Autologous dendritic cells |
Recruiting |
Study Name: Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma Condition: Glioblastoma (GBM) DIPG Date: 2016-04-27 Interventions: Drug: Doxorubicin |
Recruiting |
Study Name: Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma Condition: Glioma Date: 2016-02-22 Interventions: Drug: LBH589 Patients with recurrent/progressive DIPG will be enrolled at the time of progression. Thera |