Status | Study |
Not yet recruiting |
Study Name: Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease Condition: Cardiac TTR Amyloidosis Date: 2017-03-28 Interventions: Diagnostic Test: Tc99m-labeled pyrophosphate scan Intravenous injection of Tc99m-labeled pyrophosphate w |
Available |
Study Name: Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR) Condition: TTR-mediated Amyloidosis Amyloidosis, Hereditary Amyloid N Date: 2016-10-18 Interventions: Drug: patisiran (ALN-TTR02) patisiran (ALN-TTR02) administered by intravenous (IV) infusion |
Recruiting |
Study Name: A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects Condition: Transthyretin-mediated Amyloidosis (ATTR Amyloidosis) Date: 2016-05-18 Interventions: Drug: ALN-TTRSC02 Ascending do |
Recruiting |
Study Name: Carpal Tunnel Syndrome and Amyloid Cardiomyopathy Condition: Amyloidosis Cardiomyopathy Transthyr Date: 2016-04-20 |
Withdrawn |
Study Name: The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart Condition: Amyloidosis Date: 2015-11-19 Interventions: Drug: Isis 420915/GSK 299872 Open label study in comparison to historic control. |
Enrolling by invitation |
Study Name: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran) Condition: Amyloidosis Date: 2015-07-16 Interventions: Drug: Patisiran (ALN-TTR02) administered by intravenous (IV) infusion |
Active, not recruiting |
Study Name: ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) Condition: Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) Amyloidosis, Heredita Date: 2014-12-12 Interventions: Drug: Revusiran (ALN-TTRSC) Drug: Sterile |
Recruiting |
Study Name: Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement. Condition: Heart Disease Aging Amyloidosis Date: 2014-10-06 Interventions: Other: a basal LV septum biopsy During surgery, a basal LV septum biopsy will be collected for determina |
Completed |
Study Name: Study of SOM0226 in Familial Amyloid Polyneuropathy Condition: Familial Amyloid Polyneuropathy (FAP) Date: 2014-07-09 Interventions: Drug: SOM0226 Oral |
Enrolling by invitation |
Study Name: Open-Label Extension Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP) Condition: FAP Familial Amyloid Polyneuropathy Date: 2014-06-12 Interventions: Drug: IONIS-TTR Rx 300 mg IONIS-TTR Rx administered once weekly |