Status | Study |
Recruiting |
Study Name: Safety and Efficacy Study of Gene Therapy for The Treatment of Leber's Hereditary Optic Neuropathy Condition: Leber Hereditary Optic Neuropathy Date: 2017-05-10 Interventions: Drug: rAAV2-ND4 a Single IVT I |
Recruiting |
Study Name: Stem Cell Ophthalmology Treatment Study II Condition: Retinal Disease Age-Related Macular Degeneration Retinitis Date: 2017-01-01 Interventions: Procedure: Arm 1 |
Recruiting |
Study Name: Biomechanics of Optic Neuropathy Condition: Optic Neuropathy Date: 2016-08-28 Interventions: Device: magnetic resonance image (MRI) |
Recruiting |
Study Name: Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON) Condition: Leber's Hereditary Optic Neuropathy (LHON) Date: 2016-06-07 |
Recruiting |
Study Name: Study to Assess the Efficacy and Safety of Raxone in LHON Patients Condition: Leber's Hereditary Optic Neuropathy (LHON) Date: 2016-05-12 Interventions: Drug: Idebenone Other Name: Raxone |
Recruiting |
Study Name: Post Authorisation Safety Study With Raxone in LHON Patients Condition: Leber's Hereditary Optic Neuropathy (LHON) Date: 2016-04-25 Interventions: Drug: Idebenone Raxone 900mg/day as per Raxone SmPC and medical judgement of treating physician. |
Active, not recruiting |
Study Name: A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide (MTP-131) Topical Ophthalmic Solution for the Treatment of Leber's Hereditary Optic Neuropathy Condition: Leber's Hereditary Optic Neuropathy Date: 2016-02-15 Interventions: Drug: elamipretide (MTP-131) 1% topical ophthalmic solution |
Active, not recruiting |
Study Name: Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation Condition: Optic, Atrophy, Hereditary, Leber Date: 2016-01-07 Interventions: Genetic: GS010 |
Recruiting |
Study Name: Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation Condition: Optic, Atrophy, Hereditary, Leber Date: 2016-01-07 Interventions: Genetic: GS010 |
No longer available |
Study Name: Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON] Condition: Leber's Hereditary Optic Neuropathy Date: 2014-11-21 Interventions: Drug: EPI-743 EPI-743 is a quinone oxidation product of alpha-tocotrienol |