Small vessel disease is a condition in which the small arteries in the heart become narrowed. Small vessel disease causes signs and symptoms of heart disease, such as chest pain (angina).
Small vessel disease is sometimes called coronary microvascular disease or small vessel heart disease. It's usually diagnosed after a doctor checks for blockages in the main arteries of the heart but finds little or no narrowing in the large vessels, even though your symptoms persist.
Although anyone can have small vessel disease, it's more common in women and in people who have diabetes or high blood pressure. Small vessel disease is treatable but can be difficult to detect.
Source: http://www.mayoclinic.com
Small vessel disease symptoms include:
If you've been treated for coronary artery disease with angioplasty and stents and your signs and symptoms haven't gone away, you may also have small vessel disease.
If you're having chest pain along with other signs and symptoms — such as shortness of breath, sweating, nausea, dizziness, or pain that radiates beyond your chest to one or both of your arms or your neck — seek emergency medical care immediately.
If you're having symptoms such as fatigue and abdominal pain, it might be difficult to tell if your signs and symptoms are due to small vessel disease, but if you have chest pain, see your doctor to find out the cause.
Source: http://www.mayoclinic.com
While the larger arteries in the heart are responsible for pumping blood through your heart, the small vessels expand when you're active and then contract while you're at rest.
The large vessels in your heart can become narrowed or blocked through atherosclerosis, a condition in which fatty deposits build up in the arteries. In small vessel disease, the narrowing of the small vessels in the heart makes it so they can't expand properly when you're active. As a result, you don't get an adequate supply of oxygen-rich blood. This inability to expand is called endothelial dysfunction. This problem may cause your small vessels to actually become smaller when you're active or under emotional stress. The reduced blood flow through the small vessels causes chest pain and other symptoms similar to those you'd have if you were having angina or a heart attack.
Source: http://www.mayoclinic.com
Because large vessel coronary artery disease and small vessel disease have the same signs and symptoms, it's likely you'll be tested for large vessel coronary artery disease by checking the main arteries in your heart first. If no problems are found, then your doctor may do additional tests for small vessel disease.
To diagnose small vessel disease, you'll need a physical exam. Your doctor will also ask you about your medical history and any family history of heart disease. Your doctor will likely check your cholesterol levels to see if high cholesterol could be clogging your arteries and causing chest pain.
The tests for small vessel disease are similar to those for other types of heart disease and include:
If your doctor can't find any blockages in your main arteries based on these tests, you'll have an additional test to check for blockages in the smaller arteries of your heart:
Source: http://www.mayoclinic.com
Because small vessel disease can make it harder for the heart to pump blood to the rest of the body, small vessel disease can cause serious problems if left untreated, such as:
Source: http://www.mayoclinic.com
There haven't been any scientific studies to show what you can do to prevent small vessel disease, but it seems that controlling the disease's major risk factors — high blood pressure, high cholesterol and obesity — can help. Things you can do that may help reduce your risk include:
Source: http://www.mayoclinic.com
Dietary supplements that may be helpful for people with small vessel disease include:
As with any other alternative therapy, talk to your doctor before adding any supplements to your treatment to ensure that they won't interfere with any medications you're already taking.
Source: http://www.mayoclinic.com
Risk factors for small vessel disease include:
It's not clear why the same risk factors, such as obesity or an inactive lifestyle, cause some people to develop small vessel disease instead of large vessel coronary artery disease.
Source: http://www.mayoclinic.com
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