Disease: Peripheral artery disease

Overview

Peripheral artery disease (also called peripheral arterial disease) is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs.

When you develop peripheral artery disease (PAD), your extremities — usually your legs — don't receive enough blood flow to keep up with demand. This causes symptoms, most notably leg pain when walking (claudication).

Peripheral artery disease is also likely to be a sign of a more widespread accumulation of fatty deposits in your arteries (atherosclerosis). This condition may be reducing blood flow to your heart and brain, as well as your legs.

You often can successfully treat peripheral artery disease by quitting tobacco, exercising and eating a healthy diet.

Source: http://www.mayoclinic.com

Symptoms

While many people with peripheral artery disease have mild or no symptoms, some people have leg pain when walking (claudication).

Claudication symptoms include muscle pain or cramping in your legs or arms that's triggered by activity, such as walking, but disappears after a few minutes of rest. The location of the pain depends on the location of the clogged or narrowed artery. Calf pain is the most common location.

The severity of claudication varies widely, from mild discomfort to debilitating pain. Severe claudication can make it hard for you to walk or do other types of physical activity.

When to see a doctor

If you have leg pain, numbness or other symptoms, don't dismiss them as a normal part of aging. Call your doctor and make an appointment.

Even if you don't have symptoms of peripheral artery disease, you may need to be screened if you are:

  • Over age 70
  • Over age 50 and have a history of diabetes or smoking
  • Under age 50, but have diabetes and other peripheral artery disease risk factors, such as obesity or high blood pressure

Source: http://www.mayoclinic.com

Causes

Peripheral artery disease is often caused by atherosclerosis. In atherosclerosis, fatty deposits (plaques) build up in your artery walls and reduce blood flow.

Although the heart is usually the focus of discussion of atherosclerosis, this disease can and usually does affect arteries throughout your body. When it occurs in the arteries supplying blood to your limbs, it causes peripheral artery disease.

Less commonly, the cause of peripheral artery disease may be blood vessel inflammation, injury to your limbs, unusual anatomy of your ligaments or muscles, or radiation exposure.

Source: http://www.mayoclinic.com

Diagnosis

Some of the tests your doctor may rely on to diagnose peripheral artery disease are:

  • Physical exam. Your doctor may find signs of PAD during a physical examination, such as a weak or absent pulse below a narrowed area of your artery, whooshing sounds (bruits) over your arteries that can be heard with a stethoscope, evidence of poor wound healing in the area where your blood flow is restricted, and decreased blood pressure in your affected limb.
  • Ankle-brachial index (ABI). This is a common test used to diagnose PAD. It compares the blood pressure in your ankle with the blood pressure in your arm.

    To get a blood pressure reading, your doctor uses a regular blood pressure cuff and a special ultrasound device to evaluate blood pressure and flow.

    You may walk on a treadmill and have readings taken before and immediately after exercising to capture the severity of the narrowed arteries during walking.

  • Ultrasound. Special ultrasound imaging techniques, such as Doppler ultrasound, can help your doctor evaluate blood flow through your blood vessels and identify blocked or narrowed arteries.
  • Angiography. By injecting a dye (contrast material) into your blood vessels, this test allows your doctor to view blood flow through your arteries as it happens. Your doctor is able to trace the flow of the contrast material using imaging techniques, such as X-ray imaging or procedures called magnetic resonance angiography (MRA) or computerized tomography angiography (CTA).

    Catheter angiography is a more invasive procedure that involves guiding a catheter through an artery in your groin to the affected area and injecting the dye that way. Although invasive, this type of angiography allows for simultaneous diagnosis and treatment — finding the narrowed area of a blood vessel and then widening it with a dilating procedure or administering medication to improve blood flow.

  • Blood tests. A sample of your blood can be used to measure your cholesterol and triglycerides and to check for diabetes.

Source: http://www.mayoclinic.com

Complications

If your peripheral artery disease is caused by a buildup of plaques in your blood vessels (atherosclerosis), you're also at risk of developing:

  • Critical limb ischemia. This condition begins as open sores that don't heal, an injury, or an infection of your feet or legs. Critical limb ischemia occurs when such injuries or infections progress and can cause tissue death (gangrene), sometimes requiring amputation of the affected limb.
  • Stroke and heart attack. The atherosclerosis that causes the signs and symptoms of peripheral artery disease isn't limited to your legs. Fat deposits also build up in arteries supplying your heart and brain.

Source: http://www.mayoclinic.com

Prevention

The best way to prevent claudication is to maintain a healthy lifestyle. That means:

  • Quit smoking if you're a smoker.
  • If you have diabetes, keep your blood sugar in good control.
  • Exercise regularly. Aim for 30 minutes several times a week after you have gotten your doctor's OK.
  • Lower your cholesterol and blood pressure levels, if applicable.
  • Eat foods that are low in saturated fat.
  • Maintain a healthy weight.

Source: http://www.mayoclinic.com

Alternative medicine

The blood-thinning effects of ginkgo may allow people with intermittent claudication to walk longer distances with less pain. However, this herbal remedy can cause bleeding when taken in high doses, and it could be dangerous if paired with anti-platelet medications, including aspirin, which are commonly prescribed to people with PAD.

Talk to your doctor before you consider taking ginkgo for relief from leg pain.

Source: http://www.mayoclinic.com

Lifestyle and home remedies

Many people can manage the symptoms of peripheral artery disease and stop the progression of the disease through lifestyle changes, especially quitting smoking. To stabilize or improve PAD:

  • Stop smoking. Smoking contributes to constriction and damage of your arteries and is a significant risk factor for the development and worsening of PAD. If you smoke, quitting is the most important thing you can do to reduce your risk of complications.

    If you're having trouble quitting on your own, ask your doctor about smoking cessation options, including medications to help you quit.

  • Exercise. This is a key component. Success in treatment of PAD is often measured by how far you can walk without pain. Proper exercise helps condition your muscles to use oxygen more efficiently.

    Your doctor can help you develop an appropriate exercise plan. He or she may refer you to a claudication exercise rehabilitation program.

  • Eat a healthy diet. A heart-healthy diet low in saturated fat can help control your blood pressure and cholesterol levels, which contribute to atherosclerosis.
  • Avoid certain cold medications. Over-the-counter cold remedies that contain pseudoephedrine (Advil Cold & Sinus, Aleve-D Sinus & Headache, Claritin-D, Sudafed, Tylenol Cold, Zyrtec-D, others) constrict your blood vessels and may increase your PAD symptoms.

Careful foot care

In addition to the above suggestions, take good care of your feet. People with peripheral artery disease, especially those who also have diabetes, are at risk of poor healing of sores on the lower legs and feet.

Poor blood circulation can postpone or prevent proper healing and increases the risk of infection. Follow this advice to care for your feet:

  • Wash your feet daily, dry them thoroughly and moisturize often to prevent cracks that can lead to infection. Don't moisturize between the toes, however, as this can encourage fungal growth.
  • Wear well-fitting shoes and thick, dry socks.
  • Promptly treat any fungal infections of the feet, such as athlete's foot.
  • Take care when trimming your nails.
  • Inspect your feet daily for injuries.
  • Have a foot doctor (podiatrist) treat bunions, corns or calluses.
  • See your doctor at the first sign of a sore or injury to your skin.

Source: http://www.mayoclinic.com

Coping and support

Peripheral artery disease can be frustrating, especially when the exercise that will help you get better causes you pain. Don't get discouraged, however. As you continue exercising, you'll increase the distance you can walk without pain.

You may find it helpful to raise the head of your bed by 4 to 6 inches (10 to 15 centimeters), because keeping your legs below the level of your heart usually lessens pain.

Another tip for reducing your symptoms is to avoid cold temperatures as much as possible. If you can't avoid the cold, be sure to dress in warm layers.

Source: http://www.mayoclinic.com

Risk factors

Factors that increase your risk of developing peripheral artery disease include:

  • Smoking
  • Diabetes
  • Obesity (a body mass index over 30)
  • High blood pressure
  • High cholesterol
  • Increasing age, especially after reaching 50 years of age
  • A family history of peripheral artery disease, heart disease or stroke
  • High levels of homocysteine, a protein component that helps build and maintain tissue

People who smoke or have diabetes have the greatest risk of developing peripheral artery disease due to reduced blood flow.

Source: http://www.mayoclinic.com

Define Common Diseases

Welcome to WebHealthNetwork, here you can find information, definitaions and treatement options for most common diseases, sicknesses, illnesses and medical conditions. Find what diseases you have quick and now.