What is insomnia and what causes it?
Insomnia is difficulty falling or staying asleep, the absence of restful sleep, or poor quality of sleep. Insomnia is a symptom and not a disease. The most common causes of insomnia are:
Insomnia can also be caused by poor sleeping habits such as excessive daytime naps or caffeine consumption and poor sleep hygiene.
The American Academy of Sleep Medicine estimates 30% of adults have some symptoms of insomnia, 10% have insomnia symptoms so severe they cause consequences such as daytime sleepiness, and less than 10% have chronic insomnia.
Insomnia may be classified by how long the symptoms are present.
Transient insomnia may progress to short-term insomnia and without adequate treatment short-term insomnia may become chronic insomnia.
Some of the medications and substances that can contribute to insomnia are:
Learn more about: Lasix | Dyazide | Wellbutrin | Wellbutrin SR | Wellbutrin XL | Zyban | Prozac | Meridia | Fastin
Insomnia also may be the result of withdrawal from:Insomnia can also result from poor sleep-related habits (poor sleep hygiene).
Learn more about: Valium | Librium | Ativan | cocaine
What are natural treatments for insomnia?
There are several ways insomnia may be treated without use of medication. These include behavioral modification and use of natural herbal remedies.
When a person consults a doctor about insomnia, they may be asked to keep a sleep log for several weeks to monitor sleep habits. The treatment options for short-term or chronic insomnia include not only medications, but often sleep habit and behavioral modifications for optimal long-term results.
Evaluating sleep habits is important in the management of insomnia. Treatment of underlying sleep disorders and in some instances, changing sleep habits may correct the problem without the need for medications. Good sleep habits (also referred to as good sleep hygiene) should include:
Melatonin
Melatonin (for example, Melatonex) is the only hormone available OTC for insomnia. Melatonin is a hormone produced by the pineal gland that helps regulate the body's clock or sleep-wake cycle. The secretion of melatonin is increased by darkness and decreased by light. The exact mechanism of how melatonin induces sleep has not been determined. Melatonin also decreases mental alertness and body temperature.
Melatonin is sold as a dietary supplement and is, therefore, not regulated by the FDA. It is commonly used for jet lag, insomnia, and sleep disturbances related to working night shifts. Some limited evidence suggests melatonin may be useful for treating sleep disturbances.
In 2005, MIT analyzed 17 peer-reviewed studies using melatonin. The analysis showed that melatonin was effective in helping people fall asleep at doses of 0.3 milligrams (mg). In some preparations the dosage of melatonin is significantly higher and these larger doses have shown to be less effective after only a few days of use.
If a person would like to try melatonin tablets, consult a doctor first.
Dosing: There is no established dose or time of administration. Individuals should follow the product labeling for dosing and administration.
Pregnancy and lactation: The use of melatonin during pregnancy or lactation has not been studied adequately. At high doses (more than 300 mg), melatonin may affect contraception (birth control) and increase levels of prolactin in the body. Based on past experience with other agents and the possibility of unknown risks to the fetus, melatonin should be avoided during pregnancy while breastfeeding. Consult your doctor before you use melatonin if you are pregnant or breastfeeding.
Children: The use of melatonin in children may be effective, particularly in children with disturbed sleep due to autism spectrum disorders. However, it should not be used as a first-choice treatment in children. Consult your pediatrician before giving your child melatonin for sleep.
Drug interactions: Although melatonin is sold as a dietary supplement, it should be thought of as a drug. It has side effects and may have drug interactions that have not been identified. The level of melatonin that the body produces is increased by certain drugs, such as selective serotonin reuptake inhibitor antidepressants or SRRIs (for example, fluoxetine [Prozac], sertraline [Zoloft], paroxetine [Paxil]) and monoamine oxidase inhibitors (for example, tranylcypromine [Parnate], phenelzine [Nardil]). The interaction between these antidepressants and melatonin used as a sleeping aid has not been assessed.
Learn more about: Zoloft | Paxil | Parnate | Nardil
Side effects: The most common adverse effect of melatonin is drowsiness. Therefore, tasks that require alertness (for example, driving) should be avoided for four to five hours after taking melatonin. Melatonin also may also cause itching, abnormal heartbeats, and headaches. Melatonin appears to be safe when used short-term (less than three months). Long-term side effects of melatonin are unkown.
Melatonin is either derived from animal sources or synthesized in a laboratory. Melatonin obtained from animal sources has a higher likelihood of contamination, which can cause allergic reactions and viral transmission, than synthetic melatonin.
Melatonin may stimulate the immune system. People with severe allergies or other disorders that may be caused by an overactive immune system (for example, systemic lupus erythematosus, rheumatoid arthritis) should avoid using melatonin.
Other herbal products: Natural herbal supplements such as valerian, chamomile, kava kava, and others have been touted as remedies for insomnia; however, the safety or effectiveness of these products has not been documented. Consult your doctor before taking any herbal supplements to treat insomnia.
What over-the-counter (OTC) medicines are there for insomnia?
Self-treatment of insomnia with over-the-counter (OTC) drugs is advisable only for transient or short-term insomnia. OTC sleep aids should only be used for a short period of time in conjunction with changes in sleeping habits. Chronic use of these drugs may result in dependence on them. This creates a situation in which sleep is not possible unless the drug is used. Chronic insomnia should be evaluated by a physician.
Antihistamines
Diphenhydramine (for example, Sominex, Nytol) and doxylamine (for example, Unisom) are antihistamines currently marketed as OTC sleep aids. Diphenhydramine is the only agent considered to be safe and effective by the Food and Drug Administration. Other uses for diphenhydramine include allergies, motion sickness, and cough suppression. Scientists believe that diphenhydramine and doxylamine cause sedation by blocking the action of histamine in the brain, but the exact mechanism of action is not known.
If insomnia is associated with pain, there are numerous products containing a combination of an antihistamine and pain reliever. These combination products should not be used if pain is not present because the added pain reliever is not necessary.
Pregnancy and lactation: The effects of diphenhydramine and doxylamine on the fetus have not been evaluated adequately. Diphenhydramine is classified as a pregnancy "category B" drug, and is routinely safely used during pregnancy. Although the likelihood of an adverse effect on the fetus is low, sleeping agents probably should be avoided during pregnancy. Both agents may decrease lactation (production of milk). Additionally, these drugs are secreted into the breast milk, which could affect the newborn. Nursing mothers should avoid both drugs. Consult a physician if you are pregnant and have insomnia.
Children: Children less than 12 years of age should not use doxylamine because its use in this in age group has not been assessed.
Elderly: Sedative effects of these drugs may interact with other potentially sedating medications. Consult a doctor before using these drugs.
Drug interactions: Diphenhydramine and doxylamine add to the sedative effects of alcohol and other medications that cause drowsiness.
Side effects: Drowsiness is the most frequent side effect of both diphenhydramine and doxylamine. These agents should not be used in situations where mental alertness is required (for example, driving). Diphenhydramine and doxylamine also cause constipation, dry mouth, and difficulty urinating. Both drugs may worsen the symptoms of glaucoma, asthma, heart problems, and prostate gland enlargement. People with these conditions should not use OTC sleep aids without consulting a physician.
Both drugs may paradoxically cause excitation, resulting in nervousness and insomnia. This occurs most often in children and the elderly.
What prescription medicines are there for insomnia?
There are numerous prescription medications options a doctor may prescribe if a person is suffering from short-term or chronic insomnia. Most are not recommended for long-term use.
Medication to treat insomnia includes several classes of drugs;
In 2007, the FDA issued a warning in regard to sedative-hypnotic drugs and their risks, which "...include severe allergic reactions and complex sleep-related behaviors, which may include sleep driving. Sleep driving is defined as driving while not fully awake after ingestion of a sedative-hypnotic product, with no memory of the event."
Learn more about: Dalmane | Restoril | ProSom
If your doctor recommends prescription sleep medications:
What are natural treatments for insomnia?
There are several ways insomnia may be treated without use of medication. These include behavioral modification and use of natural herbal remedies.
When a person consults a doctor about insomnia, they may be asked to keep a sleep log for several weeks to monitor sleep habits. The treatment options for short-term or chronic insomnia include not only medications, but often sleep habit and behavioral modifications for optimal long-term results.
Evaluating sleep habits is important in the management of insomnia. Treatment of underlying sleep disorders and in some instances, changing sleep habits may correct the problem without the need for medications. Good sleep habits (also referred to as good sleep hygiene) should include:
Melatonin
Melatonin (for example, Melatonex) is the only hormone available OTC for insomnia. Melatonin is a hormone produced by the pineal gland that helps regulate the body's clock or sleep-wake cycle. The secretion of melatonin is increased by darkness and decreased by light. The exact mechanism of how melatonin induces sleep has not been determined. Melatonin also decreases mental alertness and body temperature.
Melatonin is sold as a dietary supplement and is, therefore, not regulated by the FDA. It is commonly used for jet lag, insomnia, and sleep disturbances related to working night shifts. Some limited evidence suggests melatonin may be useful for treating sleep disturbances.
In 2005, MIT analyzed 17 peer-reviewed studies using melatonin. The analysis showed that melatonin was effective in helping people fall asleep at doses of 0.3 milligrams (mg). In some preparations the dosage of melatonin is significantly higher and these larger doses have shown to be less effective after only a few days of use.
If a person would like to try melatonin tablets, consult a doctor first.
Dosing: There is no established dose or time of administration. Individuals should follow the product labeling for dosing and administration.
Pregnancy and lactation: The use of melatonin during pregnancy or lactation has not been studied adequately. At high doses (more than 300 mg), melatonin may affect contraception (birth control) and increase levels of prolactin in the body. Based on past experience with other agents and the possibility of unknown risks to the fetus, melatonin should be avoided during pregnancy while breastfeeding. Consult your doctor before you use melatonin if you are pregnant or breastfeeding.
Children: The use of melatonin in children may be effective, particularly in children with disturbed sleep due to autism spectrum disorders. However, it should not be used as a first-choice treatment in children. Consult your pediatrician before giving your child melatonin for sleep.
Drug interactions: Although melatonin is sold as a dietary supplement, it should be thought of as a drug. It has side effects and may have drug interactions that have not been identified. The level of melatonin that the body produces is increased by certain drugs, such as selective serotonin reuptake inhibitor antidepressants or SRRIs (for example, fluoxetine [Prozac], sertraline [Zoloft], paroxetine [Paxil]) and monoamine oxidase inhibitors (for example, tranylcypromine [Parnate], phenelzine [Nardil]). The interaction between these antidepressants and melatonin used as a sleeping aid has not been assessed.
Learn more about: Zoloft | Paxil | Parnate | Nardil
Side effects: The most common adverse effect of melatonin is drowsiness. Therefore, tasks that require alertness (for example, driving) should be avoided for four to five hours after taking melatonin. Melatonin also may also cause itching, abnormal heartbeats, and headaches. Melatonin appears to be safe when used short-term (less than three months). Long-term side effects of melatonin are unkown.
Melatonin is either derived from animal sources or synthesized in a laboratory. Melatonin obtained from animal sources has a higher likelihood of contamination, which can cause allergic reactions and viral transmission, than synthetic melatonin.
Melatonin may stimulate the immune system. People with severe allergies or other disorders that may be caused by an overactive immune system (for example, systemic lupus erythematosus, rheumatoid arthritis) should avoid using melatonin.
Other herbal products: Natural herbal supplements such as valerian, chamomile, kava kava, and others have been touted as remedies for insomnia; however, the safety or effectiveness of these products has not been documented. Consult your doctor before taking any herbal supplements to treat insomnia.
What over-the-counter (OTC) medicines are there for insomnia?
Self-treatment of insomnia with over-the-counter (OTC) drugs is advisable only for transient or short-term insomnia. OTC sleep aids should only be used for a short period of time in conjunction with changes in sleeping habits. Chronic use of these drugs may result in dependence on them. This creates a situation in which sleep is not possible unless the drug is used. Chronic insomnia should be evaluated by a physician.
Antihistamines
Diphenhydramine (for example, Sominex, Nytol) and doxylamine (for example, Unisom) are antihistamines currently marketed as OTC sleep aids. Diphenhydramine is the only agent considered to be safe and effective by the Food and Drug Administration. Other uses for diphenhydramine include allergies, motion sickness, and cough suppression. Scientists believe that diphenhydramine and doxylamine cause sedation by blocking the action of histamine in the brain, but the exact mechanism of action is not known.
If insomnia is associated with pain, there are numerous products containing a combination of an antihistamine and pain reliever. These combination products should not be used if pain is not present because the added pain reliever is not necessary.
Pregnancy and lactation: The effects of diphenhydramine and doxylamine on the fetus have not been evaluated adequately. Diphenhydramine is classified as a pregnancy "category B" drug, and is routinely safely used during pregnancy. Although the likelihood of an adverse effect on the fetus is low, sleeping agents probably should be avoided during pregnancy. Both agents may decrease lactation (production of milk). Additionally, these drugs are secreted into the breast milk, which could affect the newborn. Nursing mothers should avoid both drugs. Consult a physician if you are pregnant and have insomnia.
Children: Children less than 12 years of age should not use doxylamine because its use in this in age group has not been assessed.
Elderly: Sedative effects of these drugs may interact with other potentially sedating medications. Consult a doctor before using these drugs.
Drug interactions: Diphenhydramine and doxylamine add to the sedative effects of alcohol and other medications that cause drowsiness.
Side effects: Drowsiness is the most frequent side effect of both diphenhydramine and doxylamine. These agents should not be used in situations where mental alertness is required (for example, driving). Diphenhydramine and doxylamine also cause constipation, dry mouth, and difficulty urinating. Both drugs may worsen the symptoms of glaucoma, asthma, heart problems, and prostate gland enlargement. People with these conditions should not use OTC sleep aids without consulting a physician.
Both drugs may paradoxically cause excitation, resulting in nervousness and insomnia. This occurs most often in children and the elderly.
What prescription medicines are there for insomnia?
There are numerous prescription medications options a doctor may prescribe if a person is suffering from short-term or chronic insomnia. Most are not recommended for long-term use.
Medication to treat insomnia includes several classes of drugs;
In 2007, the FDA issued a warning in regard to sedative-hypnotic drugs and their risks, which "...include severe allergic reactions and complex sleep-related behaviors, which may include sleep driving. Sleep driving is defined as driving while not fully awake after ingestion of a sedative-hypnotic product, with no memory of the event."
Learn more about: Dalmane | Restoril | ProSom
If your doctor recommends prescription sleep medications:
Source: http://www.rxlist.com
When a person consults a doctor about insomnia, they may be asked to keep a sleep log for several weeks to monitor sleep habits. The treatment options for short-term or chronic insomnia include not only medications, but often sleep habit and behavioral modifications for optimal long-term results.
Evaluating sleep habits is important in the management of insomnia. Treatment of underlying sleep disorders and in some instances, changing sleep habits may correct the problem without the need for medications. Good sleep habits (also referred to as good sleep hygiene) should include:
Source: http://www.rxlist.com
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