Drug: Seroquel, Seroquel XR (quetiapine)

What is quetiapine (Seroquel, Seroquel XR)? Quetiapine is an antipsychotic medicine. It works by changing the actions of chemicals in the brain.Quetiapine is used to treat schizophrenia in adults and children who are at least 13 years old.Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.Quetiapine is also used together with antidepressant medications to treat major depressive disorder in adults.Extended-release quetiapine (Seroquel XR) is for use only in adults and should not be given to anyone younger than 18 years old.Quetiapine may also be used for purposes not listed in this medication guide. Quetiapine 100 mg-APOround, yellow, imprinted with APO, QUE 100Quetiapine 200 mg-APOround, white, imprinted with APO, QUE 200Quetiapine 25 mg-APOround, pink, imprinted with APO, QUE 25Quetiapine 300 mg-APOcapsule, white, imprinted with APO, QUE 300Quetiapine 400 mg-APOcapsule, yellow, imprinted with APO, QUE 400Quetiapine 50 mg-APOround, white, imprinted with APO, QUE 50Seroquel 100 mground, yellow, imprinted with SEROQUEL 100Seroquel 200 mground, white, imprinted with SEROQUEL 200Seroquel 25 mground, peach, imprinted with SEROQUEL 25Seroquel 300 mgoblong, white, imprinted with SEROQUEL, 300Seroquel 400 mgoblong, yellow, imprinted with SEROQUEL, 400Seroquel 50 mground, white, imprinted with SEROQUEL 50 featuredcontentslider.init({ id: "slider1", contentsource: ["inline", ""], toc: "#increment", nextprev: ["Prev", "Next"], revealtype: "click", enablefade: [true, 0.2], autorotate: [true, 100000], onChange: function(previndex, curindex){ } })

Source: http://www.emedicinehealth.com

What are the possible side effects of quetiapine (Seroquel, Seroquel XR)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.Stop using quetiapine and call your doctor at once if you have a serious side effect such as:
  • very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors;
  • feeling like you might pass out;
  • jerky muscle movements you cannot control, trouble swallowing, problems with speech;
  • tremors, or restless muscle movements in your eyes, tongue, jaw, neck, arms, or legs;
  • mask-like appearance of the face, trouble swallowing, problems with speech;
  • blurred vision, eye pain, or seeing halos around lights;
  • increased thirst and urination, excessive hunger, fruity breath odor, weakness, nausea and vomiting; or
  • fever, chills, body aches, flu symptoms, white patches or sores inside your mouth or on your lips.
Less serious side effects may include:
  • dizziness, drowsiness, tired feeling;
  • dry mouth, sore throat;
  • stomach pain, upset stomach, nausea, vomiting, constipation;
  • breast swelling or discharge;
  • missed menstrual periods; or
  • increased appetite, weight gain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect quetiapine (Seroquel, Seroquel XR)? Before using quetiapine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by quetiapine.Tell your doctor about all other medicines you use, especially:
  • a medication to treat high blood pressure or a heart condition;
  • medications to treat Parkinson's disease;
  • steroids (prednisone and others);
  • an antibiotic or antifungal medication such as clarithromycin (Biaxin), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin, Pediazole), levofloxacin (Levaquin), ketoconazole (Nizoral), rifampin (Rifadin, Rimactane, Rifater), and others;
  • anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam);
  • heart rhythm medicine such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), disopyramide (Norpace), procainamide (Procan, Pronestyl), propafenone (Rythmol), quinidine (Quin-G), and others;
  • medications to treat HIV or AIDS;
  • migraine headache medicine such as sumatriptan (Imitrex, Treximet) or zolmitriptan (Zomig);
  • narcotic medication such as methadone (Methadose, Diskets, Dolophine);
  • seizure medication such as carbamazepine (Carbatrol, Tegretol), divalproex (Depakote), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin), or valproic acid (Depakene, Stavzor); or
  • other antidepressant or medicines to treat psychiatric disorders, such as amitriptylline (Elavil, Vanatrip, Limbitrol), clozapine (FazaClo, Clozaril), fluoxetine (Prozac, Sarafem, Symbyax), haloperidol (Haldol), risperidone (Risperdal), thioridazine (Mellaril), and others.
This list is not complete and other drugs may interact with quetiapine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Source: http://www.emedicinehealth.com

What happens if I overdose (Seroquel, Seroquel XR)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of quetiapine can be fatal. Overdose symptoms may include extreme drowsiness, fast heart rate, feeling light-headed, or fainting.

Source: http://www.emedicinehealth.com

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