Drug: Zytiga (abiraterone)

What is abiraterone (Zytiga)? Abiraterone works in the body by preventing the actions of androgens (male hormones).Abiraterone is used together with prednisone to treat prostate cancer that has spread to other parts of the body. Abiraterone may also be used for purposes not listed in this medication guide.

Source: http://www.emedicinehealth.com

What are the possible side effects of abiraterone (Zytiga)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Stop using abiraterone and call your doctor at once if you have:
  • swelling in your ankles or feet, pain in your legs;
  • rapid heartbeats, feeling short of breath (even with mild exertion);
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • pale skin, easy bruising, feeling like you might pass out;
  • upper stomach pain, itching, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes);
  • pain or burning when you urinate;
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss);
  • worsening dizziness, weakness, or tired feeling;
  • nausea, vomiting, ongoing diarrhea; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Common side effects may include:
  • swelling or discomfort in your joints;
  • mild diarrhea;
  • cough; or
  • sweating, feeling very hot.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect abiraterone (Zytiga)? Tell your doctor about all medicines you use, and those you start or stop using during your treatment with abiraterone, especially:
  • cough or cold medicine that contains dextromethorphan;
  • the heart rhythm medicines flecainide or propafenone;
  • prostate or breast cancer medications such as leuprolide, buserelin, histrelin, or goserelin;
  • thioridazine;
  • an antidepressant--amitriptyline, doxepin, clomipramine, desipramine, imipramine, nortriptyline.
This list is not complete. Other drugs may interact with abiraterone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Source: http://www.emedicinehealth.com

What happens if I overdose (Zytiga)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Source: http://www.emedicinehealth.com

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