Drug: Amturnide (aliskiren, amlodipine, and hydrochlorothiazide)

What is aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)? Aliskiren is an anti-hypertensive (blood pressure lowering) medication. It works by decreasing substances in the body that narrow blood vessels and raise blood pressure.Amlodipine is in a group of drugs called calcium channel blockers. Amlodipine relaxes (widens) blood vessels and improves blood flow.Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.The combination of aliskiren, amlodipine, and hydrochlorothiazide is used to treat high blood pressure (hypertension). This medicine is usually given after other blood pressure medications have been tried without successful treatment of symptoms.Aliskiren, amlodipine, and hydrochlorothiazide may also be used for purposes not listed in this medication guide. Amturnide 150-5-12.5 mgoval, purple, imprinted with YIY, NVRAmturnide 300-10-12.5 mgoval, red, imprinted with UIU, NVRAmturnide 300-10-25 mgoval, brown, imprinted with VIV, NVRAmturnide 300-5-12.5 mgoval, pink, imprinted with LIL, NVRAmturnide 300-5-25 mgoval, brown, imprinted with OIO, NVR featuredcontentslider.init({ id: "slider1", contentsource: ["inline", ""], toc: "#increment", nextprev: ["Prev", "Next"], revealtype: "click", enablefade: [true, 0.2], autorotate: [true, 100000], onChange: function(previndex, curindex){ } })

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What are the possible side effects of aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Stop using aliskiren, amlodipine, and hydrochlorothiazide and call your doctor at once if you have a serious side effect such as:
  • swelling in your hands, ankles, or feet;
  • feeling like you might pass out;
  • vision problems, eye pain, or seeing halos around lights;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • low sodium (headache, slurred speech, hallucinations, vomiting, severe weakness, muscle cramps, loss of coordination, feeling unsteady, seizure, fainting, shallow breathing);
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
  • mild headache;
  • dizziness; or
  • stuffy nose, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect aliskiren, amlodipine, and hydrochlorothiazide (Amturnide)? Tell your doctor about all other heart or blood pressure medications you are taking.Before using aliskiren, amlodipine, and hydrochlorothiazide, tell your doctor if you regularly use other medicines that can lower blood pressure (such as sedatives, narcotic pain medicine, sleeping pills, and medicine for seizures or anxiety). They can add to the blood pressure lowering effects of aliskiren, amlodipine, and hydrochlorothiazide.Tell your doctor about all other medicines you use, especially:
  • atorvastatin (Lipitor, Caduet) or simvastatin (Zocor, Simcor, Vytorin, Juvisync);
  • cholestyramine (Questran) or colestipol (Colestid);
  • lithium (Eskalith, Lithobid);
  • tacrolimus (Prograf);
  • insulin or oral diabetes medication;
  • all other heart or blood pressure medications you are taking, especially irbesartan (Avapro), quinidine (Quin-G), or verapamil (Calan, Covera, Isoptin, Verelan);
  • an oral, nasal, inhaled, or injectable steroid medicine;
  • any other diuretic (water pill), especially furosemide (Lasix);
  • antifungal medication such as fluconazole (Diflucan), ketoconazole (Nizoral), miconazole (Oravig), or voriconazole (Vfend);
  • HIV or AIDS medications such as nelfinavir (Viracept), ritonavir (Norvir, Kaletra), or saquinavir (Invirase); or
  • non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.
This list is not complete and other drugs may interact with aliskiren, amlodipine, and hydrochlorothiazide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Source: http://www.emedicinehealth.com

What happens if I overdose (Amturnide)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include rapid heartbeats, severe dizziness, warmth or tingly feeling, and fainting.

Source: http://www.emedicinehealth.com

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