Drug: Kazano (alogliptin and metformin)

What is alogliptin and metformin (Kazano)? Alogliptin and metformin are oral diabetes medicines that help control blood sugar levels.Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Alogliptin works by regulating the levels of insulin your body produces after eating.Alogliptin and metformin is a combination medicine used to treat type 2 diabetes. This medication is not for treating type 1 diabetes.Alogliptin and metformin may also be used for purposes not listed in this medication guide.

Source: http://www.emedicinehealth.com

What are the possible side effects of alogliptin and metformin (Kazano)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Some people develop lactic acidosis while taking alogliptin and metformin. Early symptoms may get worse over time and this condition can be fatal. Stop taking this medicine and get emergency medical help if you have even mild symptoms such as:
  • muscle pain or weakness;
  • numb or cold feeling in your arms and legs;
  • trouble breathing;
  • feeling dizzy, light-headed, tired, or very weak;
  • stomach pain, nausea with vomiting; or
  • slow or uneven heart rate.
Stop using alogliptin and call your doctor at once if you have:
  • severe pain in your upper stomach spreading to your back;
  • nausea and vomiting, loss of appetite, fast heart rate;
  • pain or burning when you urinate;
  • itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • increased blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath);
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
  • diarrhea;
  • back pain, headache; or
  • cold symptoms such as stuffy nose, sinus pain, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect alogliptin and metformin (Kazano)? Tell your doctor about all medicines you use, and those you start or stop using during your treatment with alogliptin and metformin, especially:
  • cimetidine;
  • morphine;
  • quinine;
  • ranitidine;
  • topiramate;
  • trimethoprim;
  • vancomycin;
  • zonisamide;
  • acetazolamide, methazolamide, triamterene; or
  • heart or blood pressure medication--amiloride, digoxin, procainamide, quinidine.
You may be more likely to have hyperglycemia (high blood sugar) if you take alogliptin and metformin with other drugs that can raise blood sugar, such as:
  • isoniazid;
  • a diuretic or "water pill";
  • steroids (prednisone and others);
  • phenothiazines (Compazine and others);
  • thyroid medicine (Synthroid and others);
  • birth control pills and other hormones;
  • seizure medicines (Dilantin and others);
  • diet pills; and
  • medicines to treat asthma, colds or allergies.
These lists are not complete. Other drugs may interact with alogliptin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Source: http://www.emedicinehealth.com

What happens if I overdose (Kazano)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

Source: http://www.emedicinehealth.com

Health Services in Toronto

Drug Database Online

Welcome to WebHealthNetwork an online drug guide and dictionary, here you can get drug information and definitaions for most popular pharmaceutical and medicinal drugs, and specifically Kazano (alogliptin and metformin) . Find what medications you are taking today.