Drug: Ethyol (amifostine)

What is amifostine (Ethyol)? Amifostine a chemoprotectant (KEEM-o-pro-TEK-tant) that can help lessen the side effects of certain cancer chemotherapy medications or radiation treatment.Amifostine is used to protect the kidneys from harmful effects caused by cisplatin when given to patients with ovarian cancer.Amifostine is also used to prevent severe dry mouth caused by radiation treatment of the head and neck, which can affect the salivary gland.Amifostine will not prevent all side effects of chemotherapy medications. However, this medication may help protect your body from some of the serious side effects that chemotherapy can cause.Amifostine may also be used for purposes not listed in this medication guide.

Source: http://www.emedicinehealth.com

What are the possible side effects of amifostine (Ethyol)? Get emergency medical help if you have any of these signs of an allergic reaction: hives, itching; chest tightness, difficult breathing; fever or chills; swelling of your face, lips, tongue, or throat.Some of the side effects of amifostine may occur up to several weeks after you receive this medication.Tell your caregiver right away if you have a serious side effect such as:
  • feeling like you might pass out;
  • chest pain, fast or slow heart rate;
  • weak or shallow breathing;
  • seizure (convulsions);
  • urinating less than usual or not at all;
  • severe skin rash on your stomach, back, or trunk;
  • redness, rash, or blisters on the palms of your hands or the soles of your feet; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
  • nausea, vomiting;
  • dizziness, drowsiness;
  • flushing (warmth, redness, or tingly feeling);
  • cold feeling;
  • hiccups;
  • sneezing; or
  • mild fever, general ill feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect amifostine (Ethyol)? Tell your doctor about all other medicines you use, especially medicines to treat high blood pressure.There may be other drugs that can interact with amifostine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Source: http://www.emedicinehealth.com

What happens if I overdose (Ethyol)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

Source: http://www.emedicinehealth.com

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