Drug: Eliquis (apixaban)

What is apixaban (Eliquis)? Apixaban keeps the platelets in your blood from coagulating (clotting).Apixaban is used in people with atrial fibrillation (a heart rhythm disorder) to lower the risk of stroke caused by a blood clot.Apixaban may also be used for purposes not listed in this medication guide.

Source: http://www.emedicinehealth.com

What are the possible side effects of apixaban (Eliquis)? Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have:
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop;
  • heavy menstrual periods;
  • headache, dizziness, weakness, feeling like you might pass out;
  • red, pink, or brown urine;
  • black or bloody stools, coughing up blood or vomit that looks like coffee grounds;
  • numbness, tingling, or muscle weakness (especially in your legs and feet); or
  • loss of movement in any part of your body.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: http://www.emedicinehealth.com

What other drugs will affect apixaban (Eliquis)? Tell your doctor about all medicines you use, and those you start or stop using during your treatment with apixaban, especially:
  • bosentan;
  • conivaptan;
  • cyclosporine;
  • imatinib;
  • isoniazid, rifabutin, rifampin, rifapentine;
  • nefazodone;
  • St. John's wort;
  • an antibiotic--azithromycin, clarithromycin, erythromycin, nafcillin, telithromycin;
  • antifungal medication--itraconazole, ketoconazole, posaconazole, voriconazole;
  • heart or blood pressure medication--amiodarone, captopril, carvedilol, diltiazem, dronedarone, felodipine, nicardipine, quinidine, ranolazine, verapamil;
  • the hepatitis C medications boceprevir or telaprevir;
  • HIV or AIDS medication--atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir, tipranavir; or
  • seizure medication--carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone.
Many other drugs (including some over-the-counter medicines) can increase your risk of bleeding, or your risk of developing blood clots around the brain or spinal cord during a spinal tap or epidural. It is very important to tell your doctor about all medicines you have recently used, especially:
  • dextran;
  • abciximab, eptifibatide, ticagrelor, tirofiban;
  • alteplase, reteplase, tenecteplase, urokinase;
  • anagrelide, cilostazol, clopidogrel, dipyridamole, eltrombopag, oprelvekin, prasugrel, romiplostim, ticagrelor, ticlopidine;
  • argatroban, bivalirudin, dabigatran, lepirudin, rivaroxaban;
  • dalteparin, enoxaparin, fondaparinux, heparin, tinzaparin, warfarin, Coumadin;
  • an antidepressant such as citalopram, duloxetine, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, venlafaxine, vilazodone;
  • an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others; or
  • salicylates such as aspirin, Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others.
These lists are not complete and many other medicines can interact with apixaban. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Source: http://www.emedicinehealth.com

What happens if I overdose (Eliquis)? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Source: http://www.emedicinehealth.com

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